Nevada Medicine Weekly

Nevada Medicine Weekly | December 19, 2017

News for A Healthy Nevada

Huntington's disease

Hope on the horizon for treatment of neurodegenerative disease

Dr. Ruben Dagda responds to Huntington’s disease breakthrough, discusses Parkinson’s and Alzheimer’s research

Exciting news recently emerged from the UK announcing a new treatment for Huntington's disease.

Huntington's disease (HD) is an inherited genetic disease, and according to the National Institute of Neurological Disorders and Stroke (NINDS), more than 30,000 Americans have it. A research team out of theUniversity College London has developed an experimental drug, which and uses a gene silencing technique to treat the debilitating disease. Until now, the only treatment options available have been for symptoms.

Researchers, including UNR Med Assistant Professor of Pharmacology Ruben Dagda, Ph.D., are calling this study a breakthrough in neurodegenerative diseases:

"I would say this is very promising. The particular drug, termed IONIS-HTTRx, shuts down the expression of all forms of mutant huntingtin without affecting normal huntingtin. This form of gene therapy should also work for treating other degenerative disease caused by a mutation in one gene, including many forms of spinocerebellar ataxia."

Continue reading to learn more about Huntington's disease, the experimental treatment, and Dr. Dagda's work on other neurodegenerative diseases, Parkinson's and Alzheimer's.

Announcements
Announcements

Time for faculty evaluations!

The end of the year is fast approaching, and that means it's time to fill out your 2017 faculty evaluations. Please visit the UNR Med specific faculty evaluation site. The chairs/supervisors of each department will determine their own evaluation due dates. All original and completed department packets are due to Stefani Richards by January 31, 2018.

Kudos!
Dr. Christine Cremo’s work in Science Advances offers possibility for future clinical treatment

UNR Med Professor of Pharmacology Christine Cremo, Ph.D., was part of a team of researchers who published "A mixed-kinetic model describes unloaded velocities of smooth, skeletal, and cardiac muscle myosin filaments in vitro" in Science Advances this month. The study targets key unanswered questions concerning the molecular details of how muscles generate force and motion.

Continue reading about how their approach can reveal the specific defects underlying many diseases that affect the speed and strength of muscle contraction and potentially lead to clinical treatments that restore normal function.

Collette Witt selected for Reno Sparks Chamber of Commerce 2018 Leadership class

Advancement and Engagement Events and Protocol Manager Collette Witt has been selected among 27 other area professionals to participate in Leadership Reno-Sparks, a nine-month course which provides a comprehensive view of the issues, challenges and opportunities in our region.

"I applied to this program so I could extend the depth of my knowledge of the Reno-Sparks area and discover the best ways to contribute to my community," said Witt. "I am thrilled to have been accepted to participate in this incredible professional development opportunity."

Events
Upcoming Events

Upcoming Holiday: Christmas Day

December 25, 2017

Upcoming Holiday: New Year's Day

January 1, 2018

Upcoming Holiday: Martin Luther King, Jr.'s Birthday

January 15, 2018

Events for December 19 – 26, 2017

ECHO Clinics: Pain Management

December 20, 2017 • 8–9 a.m.
Sleep and Chronic Pain

ECHO Clinics: Geriatric

December 20, 2017 • 12:15–1 p.m.
STEADI: Understanding and Assessing Fall Risk

ECHO Clinics: Diabetes and General Endocrine

December 21, 2017 • 8–9 a.m.
Minimizing Hypoglycemia

Diversity Dialogues

December 21, 2017 • 12–1 p.m.
Diversity Dialogues is an open discussion of diversity and inclusion issues and the diversity initiatives at UNR Med.

ECHO Clinics: Antibiotic Stewardship

December 21, 2017 • 12:15–1 p.m.
Cases Potpourri: Review of Topics Covered in 2017

More events

Submit an event

In The News
Latest In The News

Five Questions with DMD Researcher Dean Burkin

December 14, 2017 • MDA
Dean Burkin, professor of pharmacology and directory of cellular and molecular pharmacology and physiology graduate program at the University of Nevada, Reno School of Medicine, was awarded an MDA research grant totaling $300,000 over three years to test the effects of an existing FDA-approved drug on the function of heart and skeletal muscle in a mouse model of Duchenne muscular dystrophy (DMD).

To Unlock the Brain’s Mysteries, Purée It: A Vanderbilt neuroscientist has discovered an unusual but shockingly fruitful way to study our most enigmatic organ.

December 14, 2017 • The New York Times
In the last 12 years, Herculano-Houzel, now a researcher and professor at Vanderbilt University in Nashville, has acquired the brains of more than 130 species. She and her collaborator Christopher von Bartheld, a professor at the University of Nevada, Reno School of Medicine, published a paper last year summing up their detective work.

More In The News

Partners
Partner News

Farewell, Partnership Link

The first issue of Partnership Link was released May 6, 2015, with a goal to regularly share the news and events that highlight the partnership between the University of Nevada, Reno School of Medicine and Renown Health. While our affiliation was in its infancy, the partnership was rapidly developing, and Partnership Link was sent every week. Like any great relationship, our organizations have settled into a comfortable rhythm. Partnership Link progressed to biweekly, and then monthly.

Due to the timeliness of our partnership news, our leadership teams have decided to sunset Partnership Link in its current monthly format. Amazing partnership developments are still on the horizon, and you will hear about them as they happen through each institution's respective communications channels and through joint news releases.

To continue to stay up-to-date with the latest developments, we encourage you to subscribe to Inside Nevada Medicine, UNR Med's monthly newsletter, and Renown Health's health and wellness website, BestMedicine. We also encourage you to follow @UNRMed and @RenownHealth on your favorite social media channels. To reflect on how far we've come together, please visit the Partnership Link archive.

Continue to the final Partnership Link newsletter.

Publications
Current Newsletters

Synapse

Bi-annual magazine produced by the University of Nevada, Reno School of Medicine.

Community Faculty News

The Office for Community Faculty: Supporting those committed to educating tomorrow’s physicians.

School of Medicine Student News

Weekly newsletter for students in our medical program.

Savitt e-Minute

News and Information from the Savitt Medical Library.

Nevada Medicine Weekly is a publication of the University of Nevada, Reno School of Medicine and the office of Advancement and Engagement. Please see the Content Submissions page for instructions on how to submit items for inclusion. Copyright © 2017 University of Nevada, Reno School of Medicine.