Research

Department of Internal Medicine

Our residents are always trying out new innovative ideas and pioneering research projects not only to take medical education to the next level but also to transform patient's care.

All residents participate in at least one scholarly project during their residency as part of our curriculum and is a requirement for graduation. Our program offers several platforms for research ranging from basic science research to more clinically oriented studies and quality improvement projects. Residents typically start their projects at the beginning of each academic year and have successfully presented at various regional, national and international conferences.

We offer dedicated research time to our residents as part of non core electives in a 4-week block each academic year. Incorporating into our research culture, we have devoted the last Thursday of every month as Research Thursdays for research-related talks at our noon conference where we share ongoing projects, ideas, experimental methodologies, and resources available in the community. We also invite various eminent guest speakers giving us valuable insight into research at these talks.

University of Nevada, Reno School of Medicine

University provides residents with diverse resources ranging from bench research to library and statistical support for all the projects. School of Medicine has nearly $ 60 million in National Institutes of Health (NIH) research grants and studies related to gastrointestinal disorders, HIV, fertility, cancer, infectious diseases and battlefield injuries are currently ongoing. Savitt Medical Library provides infinite resources and has created a resident portal with pages designed specifically with our residency program in mind. Librarians closely work with our program to help residents with literature review and provide software support for most projects. University's Research Integrity Office assists our program with Institutional Research Board (IRB) related paperwork, provides resources to help avoid plagiarism and to conduct ethical research. We have committed statisticians at the University providing statistical assistance to our research projects. Some of our residents have also chosen to do Masters of Public Health (MPH) available at the University during their residency, and our program has successfully integrated this additional curriculum.

Basic Science Research:

  1. Pharmacology
  2. Physiology and Cell Biology
  3. Cellular Molecular Pharmacology Physiology
  4. Microbiology and Immunology
  5. Pathology and Laboratory Medicine

Clinical Research:

Prior publications and presentations:

2017
  • Efficacy, safety and pharmacokinetics of biosimilars of anti-tumor necrosis factor-α agents in rheumatic diseases; A systematic review and meta-analysis.
    Co-Author: Praneeth Kudaravalli
    PMID: 28209290
  • A New Treatment-integrated Prognostic Nomogram of the Barcelona Clinic Liver Cancer System for Hepatocellular Carcinoma.
    First author: Hsu CY
    PMID: 28801646
  • Comment on 'Transarterial chemo-embolisation of hepatocellular carcinoma: impact of liver function and vascular invasion'.
    Last Author: Hsu CY
    PMID: 28772280
  • Compartmentalized cAMP responses to prostaglandin EP2 receptor activation in human airway smooth muscle cells.
    Co-Author: Htun Latt
    PMID: 28603838
2016
  • Nomogram of the Barcelona Clinic Liver Cancer System: On the go.
    First author: Hsu CY
    PMID: 27744654
  • Nomogram of the Barcelona Clinic Liver Cancer System for the individual prognostic prediction in hepatocellular carcinoma.
    First author: Hsu CY
    PMID: 26972815
  • Surgical Resection is better than transarterial chemoembolization for patients with hepatocellular carcinoma beyond the Milan Criteria: A Prognostic Nomogram.
    First author: Hsu CY
    PMID: 26487000
  • Hepatocellular carcinoma patients with performance status 1 deserve new classification and treatment algorithm in the BCLC system.
    First author: Hsu CY
    PMID: 26200647
2015
  • Accuracy of detecting colorectal polyps utilizing Colon Capsule Endoscopy 2: A Meta-Analysis.
    Abstract presented at American College of Gastroenterology 80th annual meeting held in Honolulu, Hawaii, October 2015.
    Presenting author: Praneeth Kudaravalli
  • Elevated serum osteoprotegerin levels are associated with aortic valve stenosis: A Meta-Analysis.
    Abstract presented at International Academy of Cardiology, Annual Scientific Sessions, Vancouver, BC, Canada, July 2015.
    Presenting author: Praneeth Kudaravalli
  • Decreased serum vaspin levels are associated with coronary artery disease: A Meta-Analysis.
    Abstract presented at International Academy of Cardiology, Annual Scientific Sessions, Vancouver, BC, Canada, July 2015.
    Presenting author: Praneeth Kudaravalli

Contacts:

  1. Praneeth Kudaravalli, M.D.
    Chief Resident
  2. Danielle Eaton
    Director, Research Operations and Administration
  3. Mary Shultz
    Director, Savitt Medical Library
  4. Michelle Rachal, MLIS, AHIP
    Reference and Web Librarian
  5. Wei Yang Ph.D., M.D.
    Professor; Executive Director, Nevada Center for Surveys, Evaluation and Statistics (CSES)
  6. Nancy Moody, JD MA
    Director, Research Integrity Office

Renown Regional Medical Center

University of Nevada, Reno School of Medicine in collaboration with Renown Health is providing various research opportunities to internal medicine residents as part of University's efforts in bringing fascinating new research and evidence-based medicine to Northern Nevada Community. There are currently several ongoing clinical studies in various subspecialties including cardiology, neurology, critical care and oncology at Renown Health. The practice of multidisciplinary in-hospital teams has been proven to bring excellent health care and patient satisfaction; we are using this principle to bring ingenious and novel research by forming a new alliance with Renown Health Pharmacy Practice Residency and integrating our residents into pharmacy resident's research curriculum.

Clinical Research:

Sample list - Current ongoing projects:
  • Evaluate warfarin per pharmacy protocol / establishment of warfarin dosing guideline.
    Preceptor: Dr. Ward / Dr. Barcelon.
  • Evaluation and implementation of extended infusion piperacillin-tazobactam.
    Preceptor: Dr. Thompson.
  • Evaluation of quality and safety of Heparin Weight Based Protocol. Conversion of heparin weight based protocol from aPTT monitoring to anti-Xa monitoring.
    Preceptor: Dr. Barcelon / Dr. Ward.
  • Impact of Procalcitonin monitoring on inpatient antibiotic use.
    Preceptor: Dr. Thompson.
  • Assess the impact of giving push dose alteplase during cardiac arrest for suspected PE on mortality.
    Preceptor: Dr. Townsend.
  • Assess the impact of alteplase in the treatment of submassive PE on mortality, LOS, development of pulmonary HTN, and bleeding.
    Preceptor: Dr. Townsend.
  • Anticoagulation/Antiplatelet medications to beds program outcomes.
    Preceptor: Dr. Porath.
  • Assess impact of recreational marijuana approval on emergency medicine resources and narcotic utilization.
    Preceptor: Dr. Townsend.
  • IV Ketamine infusion use on pain scores and opioid use.
    Preceptor: Dr. Barcelon.
  • Adverse events associated with new biological / monoclonal antibody infusions in the outpatient setting.
    Preceptor: Dr. Zion.
  • Evaluation of ADP inhibition of patients on P2Y inhibitors and stent thrombosis.
    Preceptor: Dr. Marcus.
  • Phase III ADT+TAK-700 vs. ADT+Bicalutamide for Metastatic Prostate Cancer.
    Principal investigator: Mocherla M.D.
  • Study of Platinum+Pemetrexed chemotherapy with or without Pembrolizumab (MK-3475) in participants with first line metastatic Non-Squamous Non-Small Cell Lung Cancer (MK-3475-189/KEYNOTE-189).
    Principal investigator: Mocherla M.D.

Contacts:

  1. Michele Henderson
    Clinical Research Manager
  2. Kimberly Olsen-Wilson, MSHS, CCRP
    Clinical Research Manager
  3. Kate Ward, PharmD, BCPS
    Pharmacy Clinical Manager
  4. Jessica Thompson, PharmD, BCPS (AQ-ID)
    Infectious Diseases Pharmacy Clinical Specialist

VA Sierra Nevada Healthcare System

Veterans Healthcare System supports our goal of bringing quality patient care and advanced research to the community. Residents have access to an enormous patient database at the VA, and we provide training to learn the art of data mining headed by Dr. Elizabeth Hill. There are currently ongoing projects in quality improvement and clinical research projects in the fields of cardiology, infectious diseases, and critical care.

Contacts:

  1. Omar Canaday, M.D., FACP
    Assistant Professor of Internal Medicine
    Associate Program Director
  2. Sara Trigero, M.D.
    Deputy of Ambulatory Care
  3. Elizabeth E. Hill, Ph.D., RN
    Associate Chief of Staff, Research