Developmental Translational Team Grant

The purpose of this funding is to provide support for a clinical investigator teamed with a basic science or a pre-clinical investigator to yeild a project "proof-of-concept" for a subsequent, larger, extramural (NIH, NSF, DoD, USDA, etc.) grant application.

Eligibility to lead Developmental Team Training Project:

• A successful proposal will describe a CTR project co-directed by a clinical investigator collaborating with a basic science or preclinical investigator both with faculty appointments at Mountain West CTR-IN institutions in the same IDeA state.
• The Investigators may not concurrently serve as a Principal Investigator (PI) on an IDeA award from another IDeA program (i.e., CTR, COBRE or INBRE).

Key Dates:
Applications Due to NV INBRE: February 5, 2022
Award(s) announced: March 5, 2022
Earliest start date: September 1, 2021 (pending NIGMS approval)
Project end date (or 6 months following start date): February 1, 2023

Project Duration: Six months. No carryover beyond project period. **Funding for this project is contingent upon successful renewal of the NV INBRE grant.**

Process:
Applications submitted to the INBRE Director will include:

• a face page (fp2)
• project summary
• 2-page research strategy/concept paper
• NIH biosketch for team members
• budget and budget justification
• * See below- completed Human Subjects Form F, a copy of the IRB approval, and investigator CITI certificates.

The budget should be prepared as two separate documents with one budget identified for the CTR-IN-supported portion (i.e., clinical investigator) and one budget identified for the INBRE supported portion (basic scientist or pre-clinical investigator). This mechanism is not intended to fund new human subjects research. However, if planned preliminary data involves human subjects it should be based on data captured under a previously IRB-approved protocol (or exempt). For example, this mechanism will not support new collection of biological samples from human subjects, but it can support new analyses of biological samples that were previously collected provided that the new analysis was already approved under the existing IRB protocol. *If the proposed study involves new analyses of human subjects biological samples that were previously collected and the new analysis is approved under an existing IRB protocol, you must also submit a completed Human Subjects Form E, a copy of the IRB approval, and investigator CITI certificates.

Funding level and allowable expenses:

Total costs of up to $20,000 direct costs may be requested. Funds can be used for supplies, equipment, or travel for team or community meetings. All expenses must be allowable under NIH guidelines. Additionally, the following restrictions apply:

• Equipment costs over $5,000 - not allowable.
• Significant foreign participation - not allowable.
• Laptops/computers - not allowable.
• Tuition and fees for graduate students - not allowable. However, salary support is allowable.
• Subcontracts to institutions located in non-IDeA states - not allowable. However, services provided in non-IDeA states can be purchased on a fee-for-service basis.
• Publication costs (i.e., page charges) - not allowable.

Overall budget:

We anticipate funding up to seven projects (1 per Western IDeA state) under this announcement pending NIGMS approval. For each award CTR-IN will allocate up to $10K to support the clinical investigator half of the preclinical or clinical team, and the corresponding state INBRE program will support the basic science research investigator half of the team up to $10K.

If you have questions contact: Dr. Josh Baker (jebaker@unr.edu) or Jessica Garfield (garfieldj@med.unr.edu) Or MW CTR-IN Pilot Grant Program Dr. Curtis Noonan (curtis.noonan@mso.umt.edu) and Dr. Scott Seville (sseville@uwyo.edu)