Summary
Dr. Lee is a graduate of the Seven-Year Combined BA/MD Program at Boston University, with election to Alpha Omega Alpha Honor Medical Society. He completed his internship and residency at the Hospital of the University of Pennsylvania. He then trained in a 3-year research track fellowship in Infectious Diseases at Yale University School of Medicine, and continued at Yale as a Staff Physician at VA Connecticut Healthcare System. He also obtained his Ph.D in Investigative Medicine in the Yale Graduate School. Dr. Lee then became an Assistant Professor of Medicine in the Division of Infectious Diseases, at the University of Texas Health Science Center at San Antonio, and a member of the San Antonio Center for Medical Mycology. He subsequently joined the faculty at University of New Mexico in September of 2007, as Section Chief, Infectious Diseases at VA Albuquerque Medical Center, and Medical Director of the HIV primary care clinic. Dr. Lee was promoted to Associate Professor with tenure, then Professor and Regents' Lecturer. Dr. Lee joined the faculty at Geisel School of Medicine at Dartmouth in August 2018, as Professor of Medicine and Chief, Medicine Service at the White River Junction VA Medical Center. He has now joined the faculty at University of Nevada, Reno as Professor and Chair, Department of Internal Medicine, and Chief of Internal Medicine at Renown Health.
His research is focused on the molecular pathogenesis of invasive candidiasis and translational aspects of Candida infection, including mechanisms of biofilm formation, drug repurposing, and antifungal drug discovery. A major objective of his laboratory is to define the secretory pathways of secreted virulence proteins and determine if mutations in these pathways have an effect on biofilm formation and virulence in vivo. His lab is also involved in translational research on novel antifungal therapies and treatment approaches against biofilm formation in Candida species, including drug repurposing, high-throughput screening of small molecule compound libraries, and studies of antifungal lock therapies for prevention of catheter-associated infections. His work has been supported by the Department of Veterans Affairs Office of Research and Development, NIH NIAID, and other funding sources.